Between 1984 and 1998 vaccination dramatically reduced the

Concentrations of antibody to hepatitis B virus surface antigen (anti HBsAg) were measured two months after vaccination (peak antibody), and this and other tests for hepatitis B virus core antibody (anti HBc) and hepatitis B virus surface antigen (HBsAg) were carried out at each survey. Between 1984 and 1998 vaccination dramatically reduced the prevalence of hepatitis B virus infection in children from 48% (302/620) to 11% (68/624) in Keneba and from 80% (246/309) to 15% (34/223) in Manduar. The corresponding changes in HBsAg carriage rates were from 13% (83/622) to 1% (6/628) in Keneba and from 35% (108/309) to 2% (4/227) in Manduar..

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